Does COVID-19 affect those with Obesity more than those without it?

The simple answer seems to be yes.
Here are some statistics:
1. Those under 60 with Obesity and COVID-19 were twice as likely to be hospitalized.
2. A BMI > 40 is the second strongest independent predictor of hospitalization (age is first).
3. In China, those with Obesity had a 142% higher risk of developing severe pneumonia.
4. In France, the need for invasive mechanical ventilation (life support) was associated with a BMI of ≥35.
Those with Obesity are at a higher risk for severe lung disease with COVID-19.
Decreased chest wall compliance (how easy it is for the lungs to expand) occurs in those with Obesity. This is due to the accumulation of fat around the ribs, diaphragm, and in the abdomen. If the lungs cannot expand easily at baseline then when someone has an infection such as COVID-19 inside the lungs, then less oxygen is able to be absorbed through the lungs.
Those with Obesity may be more prone to contracting COVID-19.
The ACE2 receptor is one way of entry of COVID-19 into our cells. Imagine trying to enter a house without the doorway. ACE2 receptors are one of the doorways the virus can use to enter our bodies. Adipose tissue has ACE2 receptors and those with Obesity therefore have more receptors for entry.
Those with Obesity have a weakened immune system.
Obesity is characterized by a state of chronic and low-grade inflammation. This leads to a dysfunction of the immune system.
Those with Obesity may have multiple health conditions.
Obesity is associated with multiple chronic health problems not limited to hypertension, hyperlipidemia, non-alcoholic fatty liver disease, coronary artery disease, congestive heart failure, sleep apnea, and diabetes. These conditions have the potential to make any infection, including COVID-19, more severe.
Those with Obesity may be more contagious.
Obesity increases the duration of how long the virus is shed up to 42% longer.
In conclusion, those who struggle with Obesity have a high risk of severe infection if they contract COVID-19. This applies to more than just COVID-19 but to most other infections and diseases as well. That is why my passion is the treatment of the disease of Obesity. I am here to help. Give us a call to start treating Obesity!
Reference:
Albashir, Ahmed. (2020). The potential impacts of obesity on COVID-19. Clinical Medicine. clinmed.2020-0239. 10.7861/clinmed.2020-0239.
